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Austin Newton, a longtime professor at Princeton University and a pioneer in molecular biology, died May 13 at age 85. He was a member of the 91ÑÇÉ«´«Ã½ for 40 years.

Austin Newton

Born in Richmond, Texas, Newton graduated from the University of Texas at Austin in 1959 with a degree in chemistry, then headed to the University of California, Berkeley in 1964 where he earned a Ph.D. in biochemistry. As a postdoctoral fellow, he joined the lab of Nobel laureate Jacques Monod at the Pasteur Institute in Paris where he studied the effect of genetic mutation in E. coli.

Newton started his independent research career in 1966 as an assistant professor at Princeton where he continued his work on E. coli. He later developed an interest in asymmetric cell division, and he did extensive work in this field with his long-time collaborator and wife, Noriko Ohta. As a model system, they exploited the gram-negative, alpha-proteobacterium Caulobacter crescentus, which is widely present in fresh-water lakes and streams. Their research group focused on understanding the progression of the cell division cycle throughout successive developmental events and how multiple histidine protein kinases regulate the signal transduction pathways of C. crescentus in cell division. Newton’s work was recognized as “pioneering” and a “completely new field (that) requires vision, scientific creativity, guts, and fortitude,” in a 2009 published by Princeton.

Newton was promoted to associate professor at Princeton in 1972 and became a full professor in 1978. His research was funded by grants from the National Science Foundation and National Institutes of Health. He served in the editorial board of the Journal of Bacteriology and as an associate editor of Developmental Genetics. In 1998, he was elected as a fellow of the American Academy of Microbiology. He served as a director of graduate studies in the biology department and biochemical sciences program from 1977 to 1984 and later on as a founding member of the Department of Molecular Biology at Princeton until 1989. He retired in 2009.

In a , Newton’s colleagues and students remembered him fondly for his “scientific imagination” and “wry sense of humor.” He was passionate about sub-Saharan and West African sculpture and textiles and also loved music and art.

Newton is survived by his wife, Noriko Ohta, and his sister Margueritte Dell Austin.