91ÑÇÉ«´«Ã½

Award

Belfort strikes the right balance

She has won the 2022 91ÑÇÉ«´«Ã½ Mid-Career Leadership Award
Connor O'Hara
Dec. 2, 2021

Growing up the daughter of German immigrants in apartheid South Africa, Marlene Belfort cut open her toy dolls to get a better look at what was on the inside. She also saw her mother face the challenges of “putting in a good day’s work,” as she put it, while supporting a family. These experiences inspired Belfort to aim for success both professionally and in her home life.

Belfort-Marlene-357x376.jpg
Marlene Belfort

Her early curiosity propelled Belfort to the University of Cape Town, where she pursued an honors course that yielded her bachelor’s and master’s degrees. Some at UCT dismissed her pursuit of science degrees, as it was a common principle then that “women were for maternity, not for chemistry,” as one teaching assistant informed her. Yet her drive to learn and better herself has led her to rewarding experiences — up to and including receiving the 2022 91ÑÇÉ«´«Ã½ Mid-Career Leadership Award.

To expand her professional opportunities beyond Cape Town, Belfort decided to join her longtime boyfriend Georges in California for her doctorate. Confronted with deciding whether to stay at Northwestern University in Chicago, where she did her postdoc, the couple — now parents of three sons — took work at different organizations in the more affordable city of Albany, New York, which seemed to be “a reasonable place to raise kids and get them started” before they moved to the next stop on their journey.

“Then here we are, 43 years later,” Belfort said.

“We both needed to work extremely hard to maintain our careers,” she said, but they were also rewarded. At the translational interface between chemical engineering and biology, the Belforts have supported each other in grants, manuscripts and advising students.

“When my children were little, I kept thinking I was messing up all the time,” Belfort said, but she now believes, “having a scientific career made me a better mom, and having kids to balance out my life made me a better scientist.”

Now a distinguished professor and director of the Life Sciences Research Program at the State University of New York at Albany, Belfort said she enjoys taking care of people and organizations. She steadfastly has promoted the careers of women and underrepresented people in science and is thrilled to receive an award she describes as “particularly meaningful.”

“If I can help people strike that right balance and integrate meaningful lives with their scientific careers, that’s something that gives me great joy.”

Excising the facts about introns and inteins

Marlene Belfort said she has had a rewarding career identifying and characterizing the functional roles of both introns (noncoding intragenic sequences) and inteins (internal protein segments), molecular entities that are analogous in their ability to excise and self-splice from nucleic acids and proteins, respectively.

In her lab, Belfort studies the properties, structure, function and regulation of these entities as they relate to the behavior and evolution of organisms that contain them. With her husband, Georges Belfort, she has demonstrated applications of both entities related to biotechnology and disease, including the highly cited exploration of intein fusion for simplified protein purification methods.

Enjoy reading 91ÑÇÉ«´«Ã½ Today?

Become a member to receive the print edition four times a year and the digital edition weekly.

Learn more
Connor O'Hara

Connor O’Hara is a graduate student in the Department of Medicinal Chemistry at the School of Pharmacy at Virginia Commonwealth University. Outside of his research, he enjoys a tall pint at his local pub and the company of good friends. 

Get the latest from 91ÑÇÉ«´«Ã½ Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in People

People highlights or most popular articles

Sung honored for research; Sliger, Young named astronaut scholars
Member News

Sung honored for research; Sliger, Young named astronaut scholars

Dec. 23, 2024

Patrick Sung receives the 2024 Basser Global Prize from the Basser Center for BRCA at Penn Medicine. A foundation created by Mercury 7 astronauts awards scholarships to Shelby Sliger and Tara Young.

‘Our work is about science transforming people’s lives’
Interview

‘Our work is about science transforming people’s lives’

Dec. 17, 2024

Ann West, chair of the 91ÑÇÉ«´«Ã½ Public Affairs Advisory Committee, sits down Monica Bertagnolli, director of the National Institutes of Health.

Pernas named fellow; Heitman and Wu elected to NAM
Member News

Pernas named fellow; Heitman and Wu elected to NAM

Dec. 16, 2024

Lena Pernas is named a fellow by the David and Lucile Packard Foundation. Joseph Heitman and Hao Wu are inducted into the National Academy of Medicine.

Awards for Maquat and Gohil; Sobrado named biochem chair
Member News

Awards for Maquat and Gohil; Sobrado named biochem chair

Dec. 9, 2024

Vishal Gohil is honored for work with copper. Lynn Maquat receives two awards for RNA research. Pablo Sobrado is named endowed chair of biochemistry.

What seems dead may not be dead
Award

What seems dead may not be dead

Dec. 4, 2024

Vincent Tagliabracci will receive the Earl and Thressa Stadtman Distinguished Scientist Award at the 91ÑÇÉ«´«Ã½ Annual Meeting, April 12–15 in Chicago.

'You can't afford to be 15 years behind the parasite'
Award

'You can't afford to be 15 years behind the parasite'

Dec. 3, 2024

David Fidock will receive the Alice and C.C. Wang Award in Molecular Parasitology at the 2025 91ÑÇÉ«´«Ã½ Annual Meeting, April 12–15 in Chicago.