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Calling all scientists! The Journal of Biological Chemistry’s third annual Methods Madness tournament is finally here.

Last year’s tournament stirred up quite the rivalry, with #TeamMassSpec dethroning #TeamCryo as the #JBCMethodsMadness champion! This year we welcome new contenders, including #TeamFlow, #TeamMedicine and #TeamProtein. Will one of these newbies make it to the finals? You decide!

The madness begins on Monday, March 7. (See tournament schedule below.) Submit your bracket by Sunday, March 6, for a chance to win a $100 gift card. 

Round 1: The Scientific 16

Vote for your favorite methods by participating in polls posted by .

Monday, March 7

9 a.m. – #TeamMassSpec vs. #TeamNMR

2 p.m. – #TeamXRC vs. #TeamImmuno

Tuesday, March 8

9 a.m. – #TeamChroma vs. #TeamFRET

2 p.m. – #TeamFlow vs. #TeamPCR

Wednesday, March 9

9 a.m. – #TeamCRISPR vs. #TeamOmics

2 p.m. – #TeamSuperRes vs. #TeamOpto

Thursday, March 10

9 a.m. – #TeamCryo vs. #TeamMedicine

2 p.m. – #TeamLiveCell vs. #TeamProtein

All times Eastern.