Evolution and core processes in gene expression
June 26–29, 2025
Stowers Institute, Kansas City, Mo.
The evolution of organismal diversity and the mechanisms of gene expression are mutually dependent processes. Evolutionary processes operate at the level of gene expression, especially at the level of cis-regulatory sequences, as such changes are expected to be less pleiotropic than changes at the protein level. Conversely, cis-regulatory variation is an important component in the study of gene regulation, and identifying cis-regulatory changes that alter gene expression is key to identifying causal variants underlying human diseases.
To examine these interlinked phenomena, the meeting has an interdisciplinary focus, ranging from the fundamental mechanisms of the cis-regulatory code to the phenotypic consequences in development and evolution. Previous meetings have emphasized population and organismal level evolutionary biology, cutting-edge genomics technology and deep learning.
This year’s program adds synthetic biology as a “bottom up” dimension to these “reverse engineering” approaches as another way of studying basic mechanisms underlying gene regulation and how it evolves. The meeting will bring fresh perspectives from experts in different fields to obtain a deeper understanding of core life processes from a gene expression, developmental, and evolutionary perspective.
Important dates
May 7 | Oral abstract deadline |
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May 7 | Early registration deadline |
May 14 | Poster abstract deadline |
June 3 | Regular registration deadline |
Organizers
Speakers
- Stein Aerts, KU Leuven
- Nadav Ahituv, University of California, San Francisco
- Detlev Arendt, EMBL Heidelberg
- Žiga Avsec, DeepMind London
- Lu Bai, Pennsylvania State University
- Matthew Bennett, Rice University
- Justin Crocker, EMBL Heidelberg
- Kamena Kostova, Stowers Institute for Medical Research
- Anshul Kundaje, Stanford University
- Grace Y.C. Lee, University of California, Irvine
- Dario Lupianez, CABD Seville Spain
- Ameya Mashruwala, Stowers Institute for Medical Research
- Matt Maurano, New York University
- Heather Marlow, University of Chicago
- Joel McManus, Carnegie Mellon University
- Neşet Özel, Stowers Institute for Medical Research
- Christine Queitsch, University of Washington
- Arjun Raj, University of Pennsylvania
- Ahilya Sawh, University of Toronto
- Jianrong Wang, Michigan State University
- Corey Wilson, Georgia Institute of Technology
Location
The conference will be held at The Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110.
Health & Safety
Mask-wearing and other health and safety measures will be determined based on local, state and venue guidelines and will be communicated to attendees prior to the conference.
Visas
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