Metabolism and biosynthesis
Cellular metabolism — the chemical reactions that convert nutrients into energy and the building blocks of life — has gained attention for its role in organismal homeostasis and disease. With renewed interest in metabolism has come an appreciation for the many unknowns in the metabolic networks themselves: how metabolic pathways are regulated, how they are configured to support growth or other cellular functions, and how cells balance competing demand for metabolic intermediates. This theme will cover recent research in the basic architecture of metabolic networks, new approaches to monitoring metabolism, and insight into how these pathways contribute to disease.
Organizers
Lydia Finley
Memorial Sloan Kettering Cancer Center
Gerta Hoxhaj
University of Texas Southwestern Medical Center
Symposia
Building up: Harnessing reducing equivalents to maintain biosynthesis
- Compartmentalized NADPH metabolism: Role and regulatory mechanisms
Gerta Hoxhaj, University of Texas Southwestern Medical Center - Expanding the set of genetically encoded tools for compartment-specific manipulation of redox metabolism in living cells
Valentin Cracan, Scintillon Institute - Catabolism of extracellular GSH supplies amino acids to cells
Isaac S. Harris, University of Rochester - Mechanisms of metabolite regulation of protein function
Ed Chouchani, Harvard Medical School
Regulation of metabolic networks in health and disease
- New insights into metabolic regulation of the epigenome in cancer
Kathryn Wellen, University of Pennsylvania - Decoding nucleotide metabolism: Unveiling roles and regulations
Issam Ben–Sahra, Northwestern University - The functional outcome of Folate deficiency in effector T cells
Naama Kanarek, Harvard Medical School - Metabolism, cellular decisions and the language that unites them
Jared Rutter, University of Utah; Howard Hughes Medical Institute
Bioenergetic strategies in mammalian cells
- TCA cycle remodeling during cell state transitions
Lydia Finley, Memorial Sloan Kettering Cancer Center - Mechanisms and consequences of aspartate limitation during mitochondrial dysfunction
Lucas Sullivan, Fred Hutchinson Cancer Center - Localized real-time sensors for metabolic signaling
Lulu Cambronne, University of Texas at Austin - Measuring cancer and immune metabolism in vivo
Caroline Bartman, University of Pennsylvania
Other sessions
These sessions and activities will also be of interest. for details on these and the rest of the 91亚色传媒 Annual Meeting.
Featured speakers
Melissa J. Moore, University of Massachusetts Chan Medical School
Richard Silverman, Northwestern University
Robert N. Helsley, University of Kentucky College of Medicine
Meetups
- Industry scientists and industry interest
- Metabolism
- Proteomics and mass spec
- Plant biology and natural products
Interest group sessions
Workshops
Poster sessions
- Plant biology and natural products
- Metabolism
- Omics
Events
- 91亚色传媒 welcome address
- Career and education fair
- Emerging investigator seminar
- Undergraduate poster competition