Themes
Structural biology of proteins and subcellular structures
For decades, determining macromolecular structures has been pivotal in deciphering the complexities of biology and cell signaling. The evolution of computational methods and imaging has transformed our study of challenging macromolecules and cellular architectures. This theme will spotlight how structural biologists use complementary approaches to unveil insights into the intricacies of diverse and dynamic cellular systems that govern life itself.
Organizers
Christopher Barnes
Stanford University
Breann Brown
Vanderbilt University
Symposia
Sunday, April 13
Structural approaches to address human health
- The structural basis for receptor signaling as a blueprint for biologics
Daryl Klein, Yale University - Structural and biochemical approaches to study the nsp16-nsp10 methyltransferase from coronaviruses
Monica Rosas–Lemus, University of New Mexico - Structural characterization of bacterial lipoproteins
Naima Sharaf, Stanford University - TBD
Jonathan Abraham, Harvard University
Monday, April 14
Biomolecular complexes and allostery
- Investigating the allosteric control of heme biosynthesis
Breann Brown, Vanderbilt University - Harnessing protease conformational dynamics for detection and treatment of viral infection
Jeanne Hardy, University of Massachusetts Amherst - The intrinsic structural dynamics of a histone deacetylase enzyme dictate enzymatic activity and inhibition
D. Flemming Hansen, Francis Crick Institute - Structure and function of encapsulin nanocompartments
Tobias Giessen, University of Michigan Medical School
Tuesday, April 15
Advances in integrative structural biology
- Structure-guided approaches to engineer broad immunotherapies against emergent viruses
Christopher Barnes, Stanford University - Mapping mitochondrial protein import in cells
Danielle Grotjahn, Scripps Research Institute - Developing correlative cryo-EM technologies to support in situ structural biology
Elizabeth Wright, University of Wisconsin, Madison - Discovering and validating the biology of superdark transmembrane proteins using millions of AlphaFold2 structure predictions
Daniel Isom, University of Miami Miller School of Medicine
Other sessions
These sessions and activities will also be of interest. for details on these and the rest of the 91亚色传媒 Annual Meeting.
Featured speakers
Melissa J. Moore, University of Massachusetts Chan Medical School
Richard Silverman, Northwestern University
Rohit V. Pappu, Washington University in St. Louis
Meetups
- Cell and developmental biology
- Computational biology, predictive technology and AI
- Drug discovery and pharmacology
- Industry scientists and industry interest
- Proteins
Interest group sessions
Workshops
Poster sessions
- Cell and developmental biology
- Computational biology, predictive technology and AI
- Drug discovery and pharmacology
- Proteins
Events
- 91亚色传媒 welcome address
- Career and education fair
- Emerging investigator seminar
- Undergraduate poster competition